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2-Chloroethyl vinyl ether → 1-Cyclohexyl-4-[2-(ethenyloxy)ethoxy]benzene

HRID 2052745
ノート
印刷プレビュー

反応式

HRID 2052745 の反応式
[CH:1]1([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:14]([O:16][CH2:17][CH2:18]Cl)=[CH2:15].[OH-].[Na+].C(N(CC)CC)C>C1(C)C=CC=CC=1.[Br-].C([N+](CCCC)(CCCC)CCCC)CCC>[CH:14]([O:16][CH2:17][CH2:18][O:13][C:10]1[CH:9]=[CH:8][C:7]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)=[CH:12][CH:11]=1)=[CH2:15]
参加物実験手順後処理出典と根拠反応ノート

参加物

7

反応物 4

HCID 80742-Chloroethyl vinyl etherHCID 8471TriethylamineHCID 143274-CyclohexylphenolHCID 14798Sodium Hydroxide

生成物 1

HCID 220116871-Cyclohexyl-4-[2-(ethenyloxy)ethoxy]benzene

試薬・触媒・溶媒 2

HCID 74236Tetrabutylammonium Bromide触媒
HCID 1140
Toluene
溶媒

実験手順

In 300 ml of toluene, 83.1 g (0.5 moles) of p-cyclohexylphenol was dissolved, to which were then added 150 g of 2-chloroethyl vinyl ether, 25 g of sodium hydroxide, 5 g of tetrabutylammonium bromide and 60 g of triethylamine, and the mixture was reacted at 120° C. for 5 hours. The reaction solution was washed with water, the excessive 2-chloroethyl vinyl ether and toluene were distilled off, and the resulting oil was purified by distillation in vacuo to obtain 4-cyclohexylphenoxyethyl vinyl ether.

後処理

  1. customthe mixture was reacted at 120° C. for 5 hours
  2. washThe reaction solution was washed with water
  3. distillationthe excessive 2-chloroethyl vinyl ether and toluene were distilled off
  4. distillationthe resulting oil was purified by distillation in vacuo

出典と根拠

ORDレコード
ord-4dc4ee32008f427fa1c8df8f59595db3
出典データセット
uspto-grants-2008_02
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US07326513B2

反応ノート

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