Benzylammonium chloride → 3-Benzylaminoacrylonitrile

HRID 2058795

反応式

HRID 2058795 の反応式
[Na].O[CH:3]=[CH:4][C:5]#[N:6].Cl.[CH2:8]([NH2:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>C(#N)C>[CH2:8]([NH:15][CH:3]=[CH:4][C:5]#[N:6])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

参加物

4

反応物 2

HCID 2724127Benzylammonium chlorideHCID 86738287Sodium 3-hydroxyacrylonitrile

生成物 1

HCID 705487013-Benzylaminoacrylonitrile収率 57.1%

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

32.5 g (0.25 mol) of sodium-3-hydroxyacrylonitrile (content 70%) and 43.1 g (0.3 mol) of benzylamine hydrochloride are refluxed for 5 h in 150 ml of acetonitrile. After removal of the solid by filtration and withdrawal of the solvent, the product was dissolved in chloroform and washed with water. Subsequent vacuum distillation yielded 22.6 g of 3-benzylaminoacrylonitrile (57.1%).

後処理

  1. customAfter removal of the solid
  2. filtrationby filtration and withdrawal of the solvent
  3. dissolutionthe product was dissolved in chloroform
  4. washwashed with water
  5. distillationSubsequent vacuum distillation

出典と根拠

ORDレコード
ord-0f57112ce6d9455cb4c8af2ad9496e10
出典データセット
uspto-grants-1982_03
特許番号
US04319024

関連ノート

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