Methyl p-toluenesulfonate → Pyridinium, 4-acetyl-1-methyl-, 4-methylbenzenesulfonate (1:1)

HRID 2059497ノート

反応式

HRID 2059497 の反応式
[C:1]([C:4]1[CH:9]=[CH:8][N:7]=[CH:6][CH:5]=1)(=[O:3])[CH3:2].[CH3:10][O:11][S:12]([C:15]1[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=1)(=[O:14])=[O:13]>C(O)C>[C:18]1([CH3:21])[CH:17]=[CH:16][C:15]([S:12]([O-:14])(=[O:11])=[O:13])=[CH:20][CH:19]=1.[C:1]([C:4]1[CH:9]=[CH:8][N+:7]([CH3:10])=[CH:6][CH:5]=1)(=[O:3])[CH3:2]

参加物

4

反応物 2

HCID 6645Methyl p-toluenesulfonateHCID 142824-Acetylpyridine

生成物 1

HCID 53250141Pyridinium, 4-acetyl-1-methyl-, 4-methylbenzenesulfonate (1:1)

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

4-Acetylpyridine (30.0 g, 0.25 mol) and p-toluene sulfonic acid methyl ester (55.8 g, 0.30 mol) in 500 ml ethanol were heated under reflux for 5 hours. The solvent was removed under vacuum in a rotary evaporator and the residue was taken up in ether. After separating off the ether phase, the product slowly crystallized out. The product was dried under vacuum.

後処理

  1. temperatureunder reflux for 5 hours
  2. customThe solvent was removed under vacuum in a rotary evaporator
  3. customAfter separating off the ether phase
  4. customthe product slowly crystallized out
  5. customThe product was dried under vacuum

出典と根拠

ORDレコード
ord-8b3bc44f5cf34c75830b17b4c56ae364
出典データセット
uspto-grants-2012_10
特許番号
US08277517B2

反応ノート

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