Acetic Acid → HCID 70600924、化合物
反応式
C[O:2][CH2:3][CH2:4][C:5]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([OH:7])[CH3:6].Br.C(O)(=O)C.[OH-].[K+]>C(Cl)(Cl)Cl.O>[C:9]1([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=1[C:5]([OH:7])([CH3:6])[CH2:4][CH2:3][OH:2]参加物
7
実験手順
2.56 g. of 1-methoxy-3-p-biphenylyl-3-butanol (obtainable from 3-methoxy-1-p-biphenylyl-1-propanone and CH3MgI) is boiled for 2 hours with a mixture of 5 ml. of 48% aqueous HBr and 5 ml. of acetic acid, 10 ml. of 10% methanolic KOH are added and boiling is continued for a further 2 hours and the mixture is worked up using water and chloroform to give 3-p-biphenylyl-1,3-butanediol, m.p. 115°-117°.
出典と根拠
- ORDレコード
- ord-f9838adb5ad341599d5d8a906db53cf8
- 出典データセット
- uspto-grants-1977_09
- 特許番号
- US04049823
反応ノート
読み込み中…