4-Chloro-3-nitrobenzenesulfonamide → 4-hydrazinyl-3-nitrobenzene-1-sulfonamide

HRID 2073240ノート

反応式

HRID 2073240 の反応式
O.[NH2:2][NH2:3].Cl[C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[CH:7][C:6]=1[N+:15]([O-:17])=[O:16]>C(O)C>[N+:15]([C:6]1[CH:7]=[C:8]([S:11](=[O:13])(=[O:12])[NH2:14])[CH:9]=[CH:10][C:5]=1[NH:2][NH2:3])([O-:17])=[O:16]

参加物

4

反応物 2

HCID 73244-Chloro-3-nitrobenzenesulfonamideHCID 24654Hydrazine hydrate (1:1)

生成物 1

HCID 32513014-hydrazinyl-3-nitrobenzene-1-sulfonamide収率 93.4%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

20 ml of hydrazine hydrate were added to a suspension of 47.33 g of 4-chloro-3-nitrobenzenesulfonamide [prepared as described in: J. Am. Chem. Soc. 73, 2558 (1951)] in 200 ml of abs. ethanol. The mixture was boiled under stirring for 30 minutes, then cooled down. The crystals were filtered by suction and thoroughly washed with water to obtain 43.38 g (93.4%) of 2-nitro-4-sulfamoylphenylhydrazine, m.p.: 217°-218° C. (with decomposition).

後処理

  1. temperaturecooled down
  2. filtrationThe crystals were filtered by suction
  3. washthoroughly washed with water

出典と根拠

ORDレコード
ord-50a040bc31c94b1882c25be56ec047d6
出典データセット
uspto-grants-1990_04
特許番号
US04916149

反応ノート

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