反応式
[CH3:1][NH:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.C1(=O)CCCC1.[C-]#N.[K+].CN(C)[C:21]1([C:26]#[N:27])[CH2:25][CH2:24][CH2:23][CH2:22]1.C#N>O>[CH3:1][N:2]([CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[C:21]1([C:26]#[N:27])[CH2:25][CH2:24][CH2:23][CH2:22]1参加物
7
実験手順
The title compound (15 g; 84%) was prepared from N-methylbenzylamine (10.08 g; 83 mmol), cyclopentanone (7 g; 83 mmol) and potassium cyanide (5.41 g; 83 mmol) in water (45 ml) in a similar manner to that described in D1. 1H NMR (CDCl3) δ: 1.90 (6H, m), 2.20 (3H, s), 2.3 (2H, m), 3.62 (2H, s), 7.25 (1H, m), 7.32 (4H, m); Mass Spectrum (Electrospray LC/MS): Found 188 (MH+−HCN). C14H18N2 requires 214. Ret. time 1.21 min.
出典と根拠
- ORDレコード
- ord-3c8c8663029b447da3e44042b0133a60
- 出典データセット
- uspto-grants-2010_06
- 特許番号
- US07745642B2
関連ノート
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