Methyl iodide → 5-Butyl-2-triethylsilyl-4-furaldehyde

HRID 2081336

反応式

HRID 2081336 の反応式
[CH3:1][C:2]1OC([Si](C)(C)C)=[CH:4][C:3]=1C=O.C[Si](C)(C)C1OC=C(C=O)C=1.CI.[CH2:26]([Si:28]([CH2:38][CH3:39])([CH2:36][CH3:37])[C:29]1[O:30][CH:31]=[C:32]([CH:34]=[O:35])[CH:33]=1)[CH3:27].ICCCC>>[CH2:1]([C:31]1[O:30][C:29]([Si:28]([CH2:36][CH3:37])([CH2:26][CH3:27])[CH2:38][CH3:39])=[CH:33][C:32]=1[CH:34]=[O:35])[CH2:2][CH2:3][CH3:4]

参加物

6

反応物 5

HCID 6328Methyl iodideHCID 10962Butyl iodideHCID 108784383-Furancarboxaldehyde, 5-(triethylsilyl)-2 回HCID 156632515-(Trimethylsilyl)furan-3-carbaldehydeHCID 157445905Methyl-2-trimethylsilyl-4-furaldehyde

生成物 1

HCID 150371455-Butyl-2-triethylsilyl-4-furaldehyde

実験手順

Using the same procedure as for 5-methyl-2-trimethylsilyl-4-furaldehyde but substituting 2-trimethylsilyl-4-furaldehyde (Compound 30) and methyl iodide with 2-triethylsilyl-4-furaldehyde (Compound 31) and 1-iodobutane, respectively, gives 5-butyl-2-triethylsilyl-4-furaldehyde (Compound 41). IR (neat): 1690 cm-1; 'HNMR (CDCl3):0.73 (q, 6H, J=8.4 Hz), 0.95 (m, 12H), 1.36 (p, 2H, J=7.5 Hz), 1.69 (p, 2H, J=7.5 Hz), 2.94 (t, 2H, J=7.5 Hz), 6.89 (s, 1H) and 9.91 (s, 1H) 13CNMR (CDCl3): 3.03, 7.17, 13.6, 22.2, 26.8, 30.4, 118.6, 122.5 158.4, 170.2 and 184.8. LRMS m/e (% abundance):266 (M+, 20) 238 (20) 237 (100), 87 (10) and 75 (20); HRMS exact mass calculated for C15H26O2Si 266.1702, found 266.1690.

出典と根拠

ORDレコード
ord-986954546fb141b0aff7a11637da4bda
出典データセット
uspto-grants-1993_02
特許番号
US05183906

関連ノート

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