2-Chloroethyl vinyl ether → 1-Cyclohexyl-4-[2-(ethenyloxy)ethoxy]benzene

HRID 2085005

反応式

HRID 2085005 の反応式
[CH:1]1([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:14]([O:16][CH2:17][CH2:18]Cl)=[CH2:15].[OH-].[Na+].C(N(CC)CC)C>C1(C)C=CC=CC=1.[Br-].C([N+](CCCC)(CCCC)CCCC)CCC>[CH:14]([O:16][CH2:17][CH2:18][O:13][C:10]1[CH:9]=[CH:8][C:7]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)=[CH:12][CH:11]=1)=[CH2:15]

参加物

7

反応物 4

HCID 80742-Chloroethyl vinyl etherHCID 8471TriethylamineHCID 143274-CyclohexylphenolHCID 14798Sodium Hydroxide

生成物 1

HCID 220116871-Cyclohexyl-4-[2-(ethenyloxy)ethoxy]benzene

試薬・触媒・溶媒 2

HCID 74236Tetrabutylammonium Bromide触媒HCID 1140Toluene溶媒

実験手順

p-Cyclohexylphenol (83.1 g) (0.5 mol) was dissolved in 300 ml of toluene. Subsequently, 150 g of 2-chloroethyl vinyl ether, 25 g of sodium hydroxide, 5 g of tetrabutylammonium bromide, and 60 g of triethylamine were added to the above solution and the solution was allowed to react at 120° C. for 5 hours. The reaction solution was washed with water and the excess amounts of chloroethyl vinyl ether and toluene were distilled off. The obtained oil was purified by distillation under reduced pressure, thereby 4-cyclohexylphenoxyethyl vinyl ether was obtained.

後処理

  1. customto react at 120° C. for 5 hours
  2. washThe reaction solution was washed with water
  3. distillationthe excess amounts of chloroethyl vinyl ether and toluene were distilled off
  4. distillationThe obtained oil was purified by distillation under reduced pressure

出典と根拠

ORDレコード
ord-4589896e68224473bd3efea8e18ad43f
出典データセット
uspto-grants-2004_04
特許番号
US06720128B2

関連ノート

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