Acetic Acid → 2-(3-Aminophenyl)naphthalene
反応式
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1[CH:12]=[C:13]([N+:17]([O-])=O)[CH:14]=[CH:15][CH:16]=1.C(O)(=O)C>C(O)C.C(Cl)(Cl)Cl.[Fe]>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1[CH:12]=[C:13]([CH:14]=[CH:15][CH:16]=1)[NH2:17]参加物
6
実験手順
A mixture of 3-(2-naphthyl)-1-nitrobenzene (5.4 g), iron (3.63 g) and acetic acid (13.0 g) in ethanol (50 ml) was stirred under reflux for 3 hours. The reaction mixture was diluted with chloroform, filtered and treated with saturated sodium bicarbonate solution. The chloroform layer was separated, dried, evaporated and chromatographed on silica gel to give 3-(2-naphthyl)aniline (5.2 g).
後処理
- temperatureunder reflux for 3 hours
- filtrationfiltered
- additiontreated with saturated sodium bicarbonate solution
- customThe chloroform layer was separated
- customdried
- customevaporated
- customchromatographed on silica gel
出典と根拠
- ORDレコード
- ord-6b7dfe1c80d94d1d98741347e31b25a0
- 出典データセット
- uspto-grants-2004_04
- 特許番号
- US06727245B2
反応ノート
読み込み中…