Hexane → (E)-ethyl 3-cyclopentylacrylate
反応式
C(P([CH2:8][C:9]([O-:11])=[O:10])(CC)CC)C.[CH3:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[H-].[Na+].[CH:20]1(C=O)CCC[CH2:21]1>C1COCC1>[CH2:20]([O:11][C:9](=[O:10])/[CH:8]=[CH:12]/[CH:13]1[CH2:17][CH2:16][CH2:15][CH2:14]1)[CH3:21]参加物
6
実験手順
Following the method of example 54a, reaction of triethylphosphinoacetate (196 g, 870 mmol) with hexane-washed sodium hydride (60% in mineral oil, 35 g, 870 mmol) in THF (1200 ml) and cyclopentanecarbaldehyde (86 g, 870 mmol) in THF (300 ml) gives the title product as an oil (59.1 g). MS (m/e): 169.1 (M+H).
出典と根拠
- ORDレコード
- ord-0e2300ffdb7a4af29add24656ea50933
- 出典データセット
- uspto-grants-2009_08
- 特許番号
- US07576108B2
反応ノート
読み込み中…