Hydrazine hydrate (1:1) → 2,3-Dichloro-4-trifluoromethyl-phenylhydrazine
反応式
[Cl:1][C:2]1[C:7]([Cl:8])=[C:6](Cl)[CH:5]=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11].O.[NH2:15][NH2:16]>N1C=CC=CC=1>[Cl:8][C:7]1[C:2]([Cl:1])=[C:3]([C:10]([F:13])([F:12])[F:11])[CH:4]=[CH:5][C:6]=1[NH:15][NH2:16]参加物
4
実験手順
100 g (0.4 mol) of 2,3,4-trichlorobenzotrifluoride are initially introduced, 200 ml of pyridine and subsequently 100 g (2.0 mol) of hydrazine hydrate are added, and the mixture is then heated to the reflux temperature for 12 hours. 90% of the pyridine is then removed by distillation, and the residue remaining is stirred into 250 ml of water. The crystalline product is filtered off with suction, washed with some water and dried. 78 g (80% of theory) of 2,3-dichloro-4-trifluoromethyl-phenylhydrazine of melting point 79° to 80° C. are obtained.
後処理
- temperaturethe mixture is then heated to the reflux temperature for 12 hours
- custom90% of the pyridine is then removed by distillation
- filtrationThe crystalline product is filtered off with suction
- washwashed with some water
- customdried
出典と根拠
- ORDレコード
- ord-9c5f362dd5d644d8b11057adfd09559e
- 出典データセット
- uspto-grants-1990_06
- 特許番号
- US04936892
反応ノート
読み込み中…