3-Chlorobenzaldehyde → 3-Chlorobenzenecarbaldehyde oxime

A solution of hydroxylamine hydrochloride (3.68 g, 53 mmol) in water (5 ml) was added to a solution of 3-chlorobenzaldehyde (5.00 ml, 44 mmol) in ethanol (20 ml). A solution of sodium hydroxide (2.64 g, 66 mmol) in water (5 ml) was added. The reaction mixture was stirred at room temperature for 48 h. The reaction mixture was given onto water/ice (150 ml). The formed precipitation was isolated by filtration and dissolved in dichloromethane (200 ml). This solution was dried over magnesium sulphate. The solvent was removed to give 3.88 g of 3-chlorobenzaldehyde oxime, which was used without further purification.

1. customThe formed precipitation
2. customwas isolated by filtration
3. dry with materialThis solution was dried over magnesium sulphate
4. customThe solvent was removed

ORDレコード

ord-02a426d8c0ab434f94f4b888d1e068d5

出典データセット

uspto-grants-2009_04

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US07524813B2