1-Acetylnaphthalene → 1-(Naphthalen-1-yl)ethanone oxime

HRID 2122100

反応式

HRID 2122100 の反応式
[C:1]([C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6][CH:5]=1)(=O)[CH3:2].Cl.[NH2:15][OH:16]>N1C=CC=CC=1>[C:1](=[N:15][OH:16])([C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH:7]=[CH:6][CH:5]=1)[CH3:2]

参加物

4

反応物 2

HCID 136631-AcetylnaphthaleneHCID 443297Hydroxyamine hydrochloride

生成物 1

HCID 3496811-(Naphthalen-1-yl)ethanone oxime収率 65%

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

In a 50 ml round-bottom flask, a mixture of acetonaphthone, hydroxylamine hydrochloride in pyridine was stirred, at room temperature under nitrogen blanket, for five days. The reaction mixture was then concentrated under vacuum to remove most of pyridine. The oil was then dissolved in dichloromethane. The product precipitated on standing. The product was obtained as a white solid in 65% yield.

後処理

  1. concentrationThe reaction mixture was then concentrated under vacuum
  2. customto remove most of pyridine
  3. dissolutionThe oil was then dissolved in dichloromethane
  4. customThe product precipitated
  5. customThe product was obtained as a white solid in 65% yield

出典と根拠

ORDレコード
ord-c499d1520b644d4698af39ebe86f5379
出典データセット
uspto-grants-2004_02
特許番号
US06696608B1

関連ノート

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