Dichloromethane → 4-(5-(3-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)pyridin-2-ylamino)-6-methylisoquinolin-1-ylamino)benzonitrile

HRID 2139448

反応式

[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[CH3:112][CH2:113][N:114]([CH2:115][CH3:116])[CH2:117][CH3:118].[CH3:38][Si:39]([N-:40][Si:41]([CH3:42])([CH3:43])[CH3:44])([CH3:45])[CH3:46].[Cl:48][CH2:49][Cl:50].[Li+:47].[NH2:29][c:30]1[cH:31][cH:32][c:33]([C:34]#[N:35])[cH:36][cH:37]1.[O:58]=[C:59]([CH:60]=[CH:61][c:62]1[cH:63][cH:64][cH:65][cH:66][cH:67]1)[CH:68]=[CH:69][c:70]1[cH:71][cH:72][cH:73][cH:74][cH:75]1.[O:76]=[C:77]([CH:78]=[CH:79][c:80]1[cH:81][cH:82][cH:83][cH:84][cH:85]1)[CH:86]=[CH:87][c:88]1[cH:89][cH:90][cH:91][cH:92][cH:93]1.[O:94]=[C:95]([CH:96]=[CH:97][c:98]1[cH:99][cH:100][cH:101][cH:102][cH:103]1)[CH:104]=[CH:105][c:106]1[cH:107][cH:108][cH:109][cH:110][cH:111]1.[Pd:56].[Pd:57].[nH:1]1[n:2][cH:3][c:4]2[c:5]1[n:6][cH:7][n:8][c:9]2-[c:10]1[c:11]([NH:16][c:17]2[c:18]3[cH:19][cH:20][n:21][c:22]([Cl:28])[c:23]3[cH:24][cH:25][c:26]2[CH3:27])[n:12][cH:13][cH:14][cH:15]1>>[nH:1]1[n:2][cH:3][c:4]2[c:5]1[n:6][cH:7][n:8][c:9]2-[c:10]1[c:11]([NH:16][c:17]2[c:18]3[cH:19][cH:20][n:21][c:22]([NH:29][c:30]4[cH:31][cH:32][c:33]([C:34]#[N:35])[cH:36][cH:37]4)[c:23]3[cH:24][cH:25][c:26]2[CH3:27])[n:12][cH:13][cH:14][cH:15]1