Pyridine → tetrahydro-1-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)-3-methyl-6-phenoxycarbonyloxy-2(1H)-pyrimidinone

反応式

[Cl:19][C:20](=[O:21])[O:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[F:1][C:2]([c:3]1[n:4][n:5][c:6]([N:8]2[C:9](=[O:16])[N:10]([CH3:15])[CH2:11][CH2:12][CH:13]2[OH:14])[s:7]1)([F:17])[F:18].[cH:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1>>[F:1][C:2]([c:3]1[n:4][n:5][c:6]([N:8]2[C:9](=[O:16])[N:10]([CH3:15])[CH2:11][CH2:12][CH:13]2[O:14][C:20](=[O:21])[O:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[s:7]1)([F:17])[F:18]

参加物

反応物 3

HCID 1049Pyridine

HCID 15891Phenyl chloroformate

HCID 21400101tetrahydro-1-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)-3-methyl-6-hydroxy-2(1H)-pyrimidinone

生成物 1

HCID 21418648tetrahydro-1-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)-3-methyl-6-phenoxycarbonyloxy-2(1H)-pyrimidinone

出典と根拠

ORDレコード: ord-dc33f3383ec1417aa5b0fa3a80ff25d5
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (4/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…