Cyclopentanol → Cyclopentyl 4-methylbenzene-1-sulfonate

HRID 21480

反応式

HRID 21480 の反応式
[CH:1]1([OH:6])[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:7]1([CH3:17])[CH:12]=[CH:11][C:10]([S:13](Cl)(=[O:15])=[O:14])=[CH:9][CH:8]=1>N1C=CC=CC=1>[C:7]1([CH3:17])[CH:12]=[CH:11][C:10]([S:13]([O:6][CH:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)(=[O:15])=[O:14])=[CH:9][CH:8]=1

参加物

4

反応物 2

HCID 7298CyclopentanolHCID 73974-Toluenesulfonyl chloride

生成物 1

HCID 317685Cyclopentyl 4-methylbenzene-1-sulfonate収率 68.1%

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

Cyclopentanol (50.0 g, 0.58 mol) and p-toluenesulfonyl chloride (120 g, 0.629 mol) were dissolved in pyridine (200 ml), and the solution was poured into ice-water (about 1 liter), followed by thoroughly stirring. The precipitated solid was filtered and dried to obtain cyclopentyl p-toluenesulfonate as a white solid (94.9 g, 0.390 mol, 68.1% yield).

後処理

  1. filtrationThe precipitated solid was filtered
  2. customdried

出典と根拠

ORDレコード
ord-7763fe572c454ab3929f14c2186a331a
出典データセット
uspto-grants-1995_06
特許番号
US05424277

関連ノート

読み込み中…