1,3-Propanediol, 2-methylene- → 3-Hexadecylaminothiocarbonyloxy-2-methylenepropan-1-ol

HRID 2166427

反応式

HRID 2166427 の反応式
[CH2:1]([N:17]=[C:18]=[S:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[CH2:20]=[C:21]([CH2:24][OH:25])[CH2:22][OH:23]>CN(C)C1C=CN=CC=1.N1C=CC=CC=1>[CH2:1]([NH:17][C:18]([O:23][CH2:22][C:21](=[CH2:20])[CH2:24][OH:25])=[S:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

参加物

5

反応物 2

HCID 770481,3-Propanediol, 2-methylene-HCID 138233Hexadecyl isothiocyanate

生成物 1

HCID 540633363-Hexadecylaminothiocarbonyloxy-2-methylenepropan-1-ol

試薬・触媒・溶媒 2

HCID 142844-(Dimethylamino)pyridine触媒HCID 1049Pyridine溶媒

実験手順

Hexadecyl isothiocyanate (9.65 g) and 2-methylenepropane-1,3-diol) (3.0 g) were heated with pyridine (17 ml) and 4-dimethylaminopyridine (0.8 g) to 104° C. for 6.5 hours. The mixture was evaporated to dryness in vacuo and chromatographed on a Waters PrepLC®/System 500A using a PrepPAK®-500/SILICA cartridge with ether/chloroform/hexane 2:2:9 as eluent.

後処理

  1. customThe mixture was evaporated to dryness in vacuo
  2. customchromatographed on a Waters PrepLC®/System 500A

出典と根拠

ORDレコード
ord-818d377f8cbf4779a998dd70ca11179a
出典データセット
uspto-grants-1990_07
特許番号
US04945098

関連ノート

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