Ethanol → 4-p-Tolylsulfonyl-4-methyl-3-dimethoxymethyl-pentanoic acid

HRID 2166957

反応式

HRID 2166957 の反応式
[C:1]1([CH3:24])[CH:6]=[CH:5][C:4]([S:7]([C:10]([CH3:23])([CH3:22])[CH:11]([CH:17]([O:20][CH3:21])[O:18][CH3:19])[CH2:12][C:13]([O:15]C)=[O:14])(=[O:9])=[O:8])=[CH:3][CH:2]=1.C(O)C.[OH-].[Na+]>O>[C:1]1([CH3:24])[CH:6]=[CH:5][C:4]([S:7]([C:10]([CH3:22])([CH3:23])[CH:11]([CH:17]([O:18][CH3:19])[O:20][CH3:21])[CH2:12][C:13]([OH:15])=[O:14])(=[O:9])=[O:8])=[CH:3][CH:2]=1

参加物

5

反応物 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 12850320Methyl 4-p-tolylsulfonyl-4-methyl-3-dimethoxymethylpentanoate

生成物 1

HCID 128503174-p-Tolylsulfonyl-4-methyl-3-dimethoxymethyl-pentanoic acid

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

1 g of the product of Step A was added to a mixture of 20 ml of ethanol and 20 ml of aqueous 2 N sodium hydroxide solution and the mixture was refluxed for 17 hours and was cooled and poured into water. The mixture was extracted with methylene chloride and the organic phase was evaporated to dryness to obtain 4-p-tolylsulfonyl-4-methyl-3-dimethoxymethyl-pentanoic acid.

後処理

  1. temperaturethe mixture was refluxed for 17 hours
  2. temperaturewas cooled
  3. extractionThe mixture was extracted with methylene chloride
  4. customthe organic phase was evaporated to dryness

出典と根拠

ORDレコード
ord-1f8589769f9842c4948589fc9c8644e6
出典データセット
uspto-grants-1983_06
特許番号
US04390724

関連ノート

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