Isopropenyl acetate → L-Ascorbic acid, 6-acetate
反応式
[O:1]=[C:2]1[O:8][C@H:7]([C@H:9]([CH2:11][OH:12])[OH:10])[C:5]([OH:6])=[C:3]1[OH:4].[C:13](OC(C)=C)(=[O:15])[CH3:14]>O1CCCC1>[C:13]([O:12][CH2:11][C@H:9]([OH:10])[C@H:7]1[O:8][C:2](=[O:1])[C:3]([OH:4])=[C:5]1[OH:6])(=[O:15])[CH3:14]参加物
4
実験手順
Four grams of the immobilized Lipase PS prepared by the same procedure as in Example 2 was added to 40 ml of a dry tetrahydrofuran solution containing 4 g of ascorbic acid and 3 g of isopropenyl acetate, and then the reaction was continued for 22 hours at 40° C. The reaction mixture was then filtered, concentrated and recrystallized from acetone-benzene to yield 4.5 g of ascorbic acid-6-acetate. The water content of the reaction system was 700 ppm.
後処理
- customFour grams of the immobilized Lipase PS prepared by the same procedure as in Example 2
- filtrationThe reaction mixture was then filtered
- concentrationconcentrated
- customrecrystallized from acetone-benzene
出典と根拠
- ORDレコード
- ord-002b67edca0b41cc91588809d02fec50
- 出典データセット
- uspto-grants-1995_10
- 特許番号
- US05455174
反応ノート
読み込み中…