Hydrazine hydrate (1:1) → HCID 178509225、化合物

HRID 2214737ノート

反応式

HRID 2214737 の反応式
O.[NH2:2][NH2:3].Cl[C:5]1[N:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:9][C:6]=1[C:7]#[N:8]>N1C=CC=CC=1>[C:13]1([C:10]2[CH:9]=[C:6]3[C:7]([NH2:8])=[N:3][NH:2][C:5]3=[N:12][CH:11]=2)[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 27640432-chloro-5-phenylnicotinonitrile

生成物 1

HCID 178509225HCID 178509225、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

Hydrazine hydrate (1.42 g, 28 mmol) was added to a stirred solution of 2-chloro-5-phenylnicotinonitrile (2.45 g, 11.4 mmol) in pyridine (25 ml). The reaction mixture was stirred at reflux for 6 hours, cooled and the resulting solid was filtered and dried in vacuo, affording the title compound as a solid.

後処理

  1. temperatureat reflux for 6 hours
  2. temperaturecooled
  3. filtrationthe resulting solid was filtered
  4. customdried in vacuo

出典と根拠

ORDレコード
ord-79f26bb2604840f29b7439d2cd3fb017
出典データセット
uspto-grants-2006_09
特許番号
US07109199B2

反応ノート

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