反応式
[C:1]([C:3]1[CH:13]=[CH:12][C:6]([C:7](OCC)=[O:8])=[CH:5][C:4]=1[F:14])#[N:2].[Li+].[BH4-]>C1COCC1>[F:14][C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][C:3]=1[C:1]#[N:2])[CH2:7][OH:8]参加物
4
実験手順
40 g of ethyl 4-cyano-3-fluorobenzoate in 40 ml of THF are added dropwise to a solution of 8 g of LiBH4 in 120 ml of THF. In the course of this, the reaction mixture comes to the boil. After one hour it is acidified with 2NHCl and worked up in a customary manner. 3-Fluoro-4-cyanobenzyl alcohol, m.p. 70°-72° C., is obtained.
出典と根拠
- ORDレコード
- ord-c8861f08df674d4b950967272d1f04b9
- 出典データセット
- uspto-grants-1988_11
- 特許番号
- US04784471
関連ノート
読み込み中…