m-Chloroperbenzoic acid → HCID 14329854、化合物

HRID 2232264ノート

反応式

HRID 2232264 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[CH2:11])[CH2:9][OH:10])=[CH:4][CH:3]=1.ClC1C=CC=C(C(OO)=[O:20])C=1>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([CH2:11][OH:20])[CH2:9][O:10]2)=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 70297m-Chloroperbenzoic acidHCID 106546892-(4-Chlorophenyl)prop-2-en-1-ol

生成物 1

HCID 14329854HCID 14329854、化合物収率 72.2%

試薬・触媒・溶媒 1

HCID 6212Chloroform溶媒3 回

実験手順

To a solution of the compound prepared in Example 4(c), β-(4-chlorophenyl)-β-methylene ethanol (1.05g) in chloroform (50 mL) add, with cooling, (ice bath) a solution of m-chloroperbenzoic acid (1.2g) in chloroform. Stir the chloroform solution for 4 hr. Wash the chloroform solution, successively, with aqueous 10% NaHSO3 (to remove excess per acid) followed by aqueous NaHCO3 and finally with water. Dry (Na2SO4) the chloroform solution. Remove the chloroform in vacuo to provide the title compound as a colourless oil (0.83 g). Use the title compound without any further purification in the next reaction.

後処理

  1. temperaturewith cooling
  2. washWash the chloroform solution
  3. dry with materialDry (Na2SO4) the chloroform solution
  4. customRemove the chloroform in vacuo

出典と根拠

ORDレコード
ord-9ab5f7fdd1e04bbc9b95666df4faea19
出典データセット
uspto-grants-1988_11
特許番号
US04788190

反応ノート

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