Dichloromethane → 3-fluoro-5-[3-(2-methoxy-phenyl)-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-2-[(pyridin-4-ylmethyl)-amino]-benzamide

反応式

[F:1][C:2]1[C:3]([NH:14][CH2:15][C:16]2[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=2)=[C:4]([CH:10]=[C:11](I)[CH:12]=1)[C:5]([N:7]([CH3:9])[CH3:8])=[O:6].[CH3:22][O:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[C:30]1[C:38]2[C:33](=[N:34][CH:35]=[C:36](B3OC(C)(C)C(C)(C)O3)[CH:37]=2)[N:32]([S:48]([C:51]2[CH:56]=[CH:55][C:54]([CH3:57])=[CH:53][CH:52]=2)(=[O:50])=[O:49])[CH:31]=1.ClCCl.C(=O)([O-])[O-].[Na+].[Na+]>C(#N)C>[F:1][C:2]1[C:3]([NH:14][CH2:15][C:16]2[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=2)=[C:4]([CH:10]=[C:11]([C:36]2[CH:37]=[C:38]3[C:30]([C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=4[O:23][CH3:22])=[CH:31][N:32]([S:48]([C:51]4[CH:52]=[CH:53][C:54]([CH3:57])=[CH:55][CH:56]=4)(=[O:50])=[O:49])[C:33]3=[N:34][CH:35]=2)[CH:12]=1)[C:5]([N:7]([CH3:9])[CH3:8])=[O:6]