Hydrochloric Acid → Phenylthioethanethiol

HRID 223653ノート

反応式

HRID 223653 の反応式
[C:1]1([S:7][CH2:8][CH2:9]O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1([SH:17])C=CC=CC=1.C1OC1.[OH-].[K+].NC(N)=S.Cl.O.NN>C1(C)C=CC=CC=1>[C:1]1([S:7][CH:8]([SH:17])[CH3:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

9

反応物 7

HCID 313Hydrochloric AcidHCID 6354Ethylene OxideHCID 7969ThiophenolHCID 14797Potassium HydroxideHCID 24654Hydrazine hydrate (1:1)HCID 696852-(Phenylthio)ethanolHCID 2723790Thiourea

生成物 1

HCID 23503969Phenylthioethanethiol

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

77 g of 2-phenylthioethanol, (0.5 mol, prepared from thiophenol and ethylene oxide in the presence of some potassium hydroxide) are maintained for 4 hours under reflux with 40 g of thiourea and 50 g of 37% hydrochloric acid. At 40° C., the reaction mixture is stirred with 50 g of 50% hydrazine hydrate solution for 30 minutes. 100 ml of toluene are added, this is maintained for 30 minutes in the steam bath, the toluene phase is separated off and compressed under vacuum.

後処理

  1. temperatureare maintained for 4 hours
  2. temperaturethis is maintained for 30 minutes in the steam bath
  3. customthe toluene phase is separated off

出典と根拠

ORDレコード
ord-cf8da0c2aaf54b18a49b46c8662c59e6
出典データセット
uspto-grants-1982_10
特許番号
US04355185

反応ノート

読み込み中…