Water → 4-Amino-3-bromobenzoic acid
反応式
[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[Br:11]N1C(=O)CCC1=O.O>CN(C=O)C>[NH2:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[Br:11]参加物
5
実験手順
4-Amino-benzoic acid (100 mmol) was dissolved in DMF (50 mL) and N-bromosuccinimide (100 mmol) was added. Stirred at ambient temperature for 18 h, the reaction mixture was then poured into water (100 mL). The product was removed by filtration, washed with water and dried in vacuo to give 4-amino-3-bromo-benzoic acid.
後処理
- customThe product was removed by filtration
- washwashed with water
- customdried in vacuo
出典と根拠
- ORDレコード
- ord-0bb57b91eb7849a5baba823937559782
- 出典データセット
- uspto-grants-2010_03
- 特許番号
- US07674912B2
反応ノート
読み込み中…