4-nitro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide → 4-Amino-N-[2-(diethylamino)ethyl]-2-methoxybenzamide

HRID 2262349

反応式

[N+:1]([C:4]1[CH:19]=[CH:18][C:7]([C:8]([NH:10][CH2:11][CH2:12][N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])=[O:9])=[C:6]([O:20][CH3:21])[CH:5]=1)([O-])=O>O1CCCC1.C(O)C.[Pd]>[NH2:1][C:4]1[CH:19]=[CH:18][C:7]([C:8]([NH:10][CH2:11][CH2:12][N:13]([CH2:14][CH3:15])[CH2:16][CH3:17])=[O:9])=[C:6]([O:20][CH3:21])[CH:5]=1

参加物

実験手順

5.7 g (19.3 mmol) of 4-nitro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide is dissolved in 120 ml of tetrahydrofuran:ethanol 1:1>mixed with 2 g of palladium on carbon (10%×50% water) and hydrogenated for 1 hour at room temperature and normal pressure. After being drawn off on diatomaceous earth and after concentration by evaporation, 5.45 g of 4-amino-N-(2-diethylamino-ethyl)-2-methoxy-benzamide is obtained.

後処理

concentrationafter concentration
customby evaporation

出典と根拠

ORDレコード: ord-fec49c96a0654ddaa3d16ec6f4872d02
出典データセット: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07850948B2

反応式

参加物

反応物 1

生成物 1

試薬・触媒・溶媒 2

実験手順

後処理

出典と根拠

関連ノート