Benzoyl Peroxide → Methyl 3-(bromomethyl)benzoate

HRID 226258

反応式

HRID 226258 の反応式
[CH3:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6].[Br:12]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:12][CH2:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6]

参加物

5

反応物 3

HCID 7187Benzoyl PeroxideHCID 7435Benzoic acid, 3-methyl-, methyl esterHCID 67184N-bromobutanimide

生成物 1

HCID 517981Methyl 3-(bromomethyl)benzoate

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture of 5.5 g (36 mmol) of methyl 3-methylbenzoate, 7.1 g (39.5 mmol) of N-Bromosuccinimide and 0.44 g (1.8 mmol) of benzoyl peroxide in 75 ml of Cl4C is refluxed for 5 h. The solid is filtered and washed with Cl4C. The mother liquors are concentrated and a yellow solid is obtained which is, essentially, monobromated product. This is used in the next step without further purification.

後処理

  1. temperatureis refluxed for 5 h
  2. filtrationThe solid is filtered
  3. washwashed with Cl4C
  4. concentrationThe mother liquors are concentrated
  5. customa yellow solid is obtained which
  6. customThis is used in the next step without further purification

出典と根拠

ORDレコード
ord-be0a5fcfdd5242d0a7929c42ccb8756c
出典データセット
uspto-grants-2009_07
特許番号
US07557212B2

関連ノート

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