Methanol → N-(4-Aminophenyl)propanamide
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[O:14])[CH2:12][CH3:13])=[CH:6][CH:5]=1)([O-])=O.CO>[Pd].O1CCCC1>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:10][C:11](=[O:14])[CH2:12][CH3:13])=[CH:8][CH:9]=1参加物
5
実験手順
A mixture of N-(4-nitrophenyl)propanamide (10 g, 51.5 mmol), 10% palladium on carbon (1 g), methanol (500 ml) and tetrahydrofuran (100 ml) was stirred under hydrogen atmosphere for 12 hours, insoluble substances were removed by filtration, and the filtrate was concentrated to give 8.00 g (94.8%) of the desired product as an oil.
後処理
- custominsoluble substances were removed by filtration
- concentrationthe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-1440103e8f404a808306c6bce395f453
- 出典データセット
- uspto-grants-2010_12
- 特許番号
- US07851473B2
反応ノート
読み込み中…