2-Amino-4,6-dimethyl pyrimidine → (5,7-Dimethyl-2-pyridin-2-yl-imidazo[1,2-a]-pyrimidin-3-yl)-(6-isocyanohexyl)amine
反応式
[NH2:1][C:2]1[N:7]=[C:6]([CH3:8])[CH:5]=[C:4]([CH3:9])[N:3]=1.[N+:10]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][N+:18]#[C-:19])#[C-:11].[N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[CH:26]=O>Cl(O)(=O)(=O)=O>[CH3:8][C:6]1[N:7]2[C:11]([NH:10][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][N+:18]#[C-:19])=[C:26]([C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][N:20]=3)[N:1]=[C:2]2[N:3]=[C:4]([CH3:9])[CH:5]=1参加物
5
実験手順
Compound (2) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-4,6-dimethylpyrimidine solution (0.1 M, DCM), 0.575 ml of 1,6-diisocyanhexane solution (0.2 M, DCM), 0.500 ml of pyridine-2-carbaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).