Acetaldehyde → Cyclohexyl-(2,5,7-trimethylimidazo[1,2-a]pyridin-3-yl)-amine

HRID 22804ノート

反応式

HRID 22804 の反応式
[NH2:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[C:4]([CH3:9])[N:3]=1.[CH:10]1([N+:16]#[C-:17])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1.[CH:18](=O)[CH3:19]>Cl(O)(=O)(=O)=O>[CH:10]1([NH:16][C:17]2[N:3]3[C:4]([CH3:9])=[CH:5][C:6]([CH3:8])=[CH:7][C:2]3=[N:1][C:18]=2[CH3:19])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1

参加物

5

反応物 3

HCID 177AcetaldehydeHCID 215072-Amino-4,6-dimethylpyridineHCID 79129Cyclohexyl isocyanide

生成物 1

HCID 9816566Cyclohexyl-(2,5,7-trimethylimidazo[1,2-a]pyridin-3-yl)-amine

試薬・触媒・溶媒 1

HCID 24247Perchloric Acid溶媒

実験手順

Compound (19) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-4,6-dimethylpyridine solution (0.1 M, DCM), 0.575 ml of cyclohexyl isocyanide solution (0.2 M, DCM), 0.500 ml of acetaldehyde solution (0.3 M, DCM) and 10 μl of perchloric acid (w=20%).

出典と根拠

ORDレコード
ord-793046b5752c4850a3b36506c79c4a06
出典データセット
uspto-grants-2005_02
特許番号
US06849642B2

反応ノート

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