2-Amino-4-methylpyrimidine → (2-Anthracen-9-yl-7-methylimidazo[1,2-a]pyrimidin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine

HRID 22814

反応式

HRID 22814 の反応式
[NH2:1][C:2]1[N:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]=1.[CH3:9][C:10]([N+:17]#[C-:18])([CH3:16])[CH2:11][C:12]([CH3:15])([CH3:14])[CH3:13].[CH:19]1[C:32]2[C:23](=[CH:24][C:25]3[C:30]([C:31]=2[CH:33]=O)=[CH:29][CH:28]=[CH:27][CH:26]=3)[CH:22]=[CH:21][CH:20]=1>Cl(O)(=O)(=O)=O>[CH:29]1[C:30]2[C:25](=[CH:24][C:23]3[C:32]([C:31]=2[C:33]2[N:1]=[C:2]4[N:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]4[C:18]=2[NH:17][C:10]([CH3:16])([CH3:9])[CH2:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH:26]=[CH:27][CH:28]=1

参加物

5

反応物 3

HCID 79392-Amino-4-methylpyrimidineHCID 267251,1,3,3-Tetramethylbutyl isocyanideHCID 695049-Anthracenecarboxaldehyde

生成物 1

HCID 22591919(2-Anthracen-9-yl-7-methylimidazo[1,2-a]pyrimidin-3-yl)-(1,1,3,3-tetramethylbutyl)-amine

試薬・触媒・溶媒 1

HCID 24247Perchloric Acid溶媒

実験手順

Compound (37) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-4-methylpyrimidine solution (0.1 M, DCM), 0.575 ml of 1,1,3,3-tetramethylbutyl isocyanide solution (0.2 M, DCM), 0.500 ml of anthracene-9-carbaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).

出典と根拠

ORDレコード
ord-a619d9a795b8406cbc3a945dae2c5413
出典データセット
uspto-grants-2005_02
特許番号
US06849642B2

関連ノート

読み込み中…