Ethanesulfonyl chloride → Ethanesulfonic acid;7-hydroxy-3,4-dimethylchromen-2-one

HRID 2290764ノート

反応式

HRID 2290764 の反応式
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH3:14])=[C:7]([CH3:13])[C:8](=[O:12])[O:9]2)=[CH:4][CH:3]=1.[CH2:15]([S:17](Cl)(=[O:19])=[O:18])[CH3:16]>O.[OH-].[Na+]>[CH2:15]([S:17]([OH:19])(=[O:1])=[O:18])[CH3:16].[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH3:14])=[C:7]([CH3:13])[C:8](=[O:12])[O:9]2)=[CH:4][CH:3]=1

参加物

5

反応物 2

HCID 11667Ethanesulfonyl chlorideHCID 54129907-hydroxy-3,4-dimethyl-2H-chromen-2-one

生成物 1

HCID 86741079Ethanesulfonic acid;7-hydroxy-3,4-dimethylchromen-2-one

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 14798Sodium Hydroxide溶媒

実験手順

5.0 g of 7-hydroxy-3,4-dimethylcoumarin were dissolved in 20 ml of H2O/1.1 g of NaOH at room temperature, while stirring, and 3.4 g of ethanesulfonyl chloride were added. The mixture was stirred overnight, and the precipitate was filtered off under suction and recrystallized from ethanol.

後処理

  1. stirringThe mixture was stirred overnight
  2. filtrationthe precipitate was filtered off under suction
  3. customrecrystallized from ethanol

出典と根拠

ORDレコード
ord-6ef9b4ad9f104ef58760f70b6ee8b4cf
出典データセット
uspto-grants-1986_10
特許番号
US04618622

反応ノート

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