Pyridine → HCID 21279523、化合物
反応式
[CH2:1]([S:8][C:9]1[N:10]=[C:11]2[S:16][CH2:15][CH:14](O)[N:12]2[N:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.N1C=CC=CC=1.S(Cl)(Cl)=O>ClCCl>[CH2:1]([S:8][C:9]1[N:10]=[C:11]2[S:16][CH:15]=[CH:14][N:12]2[N:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
5
実験手順
The product from stage (b) (7.9 g) was dissolved in dichloromethane (50 ml) and was treated with pyridine (2.7 g), then with thionyl chloride (4.2 g) in dichloromethane (5 ml) dropwise with stirring at 5°-10° C. After 3 hours stirring at room temperature, the solution was washed with water, dilute hydrochloric acid, aqueous sodium bicarbonate solution and water again, dried and run down to give the desired product as a brown oil which was recrystallise from ethanol to give pure product, mp 91°-93° C.
後処理
- washthe solution was washed with water, dilute hydrochloric acid, aqueous sodium bicarbonate solution and water again
- customdried
出典と根拠
- ORDレコード
- ord-18079cd7768a412ab30425b47240fd48
- 出典データセット
- uspto-grants-1989_01
- 特許番号
- US04795483
反応ノート
読み込み中…