HCID 12052140、化合物 → HCID 13883776、化合物
反応式
[N+:1]([C:4]1[CH:8]=[CH:7][N:6]([CH2:9][CH2:10][CH2:11][CH2:12][C:13]#[N:14])[N:5]=1)([O-])=O>C1COCC1.[Pd]>[NH2:1][C:4]1[CH:8]=[CH:7][N:6]([CH2:9][CH2:10][CH2:11][CH2:12][C:13]#[N:14])[N:5]=1参加物
4
実験手順
To a solution of 5-(3-nitropyrazol-1-yl)valeronitrile (9.16 g.) in dry THF (200 ml.) was added 5% w/w palladium on carbon (1.8 g.). The mixture was stirred at 20° under an atmosphere of hydrogen. 3.2 Liters of hydrogen were absorbed over 4 hours. The catalyst was filtered off and the filtrate was evaporated in vacuo to give 5-(3-aminopyrazol-1-yl)valeronitrile as an oil.
後処理
- custom3.2 Liters of hydrogen were absorbed over 4 hours
- filtrationThe catalyst was filtered off
- customthe filtrate was evaporated in vacuo
出典と根拠
- ORDレコード
- ord-e1445fdfb2d24f5ab79428792784cf8f
- 出典データセット
- uspto-grants-1989_01
- 特許番号
- US04795755
反応ノート
読み込み中…