Hydrochloric Acid → 5-Cyano-2,4-dimethoxybenzoic acid
反応式
[C:1]([C:3]1[C:4]([O:15][CH3:16])=[CH:5][C:6]([O:13][CH3:14])=[C:7]([CH:12]=1)[C:8]([O:10]C)=[O:9])#[N:2].[OH-].[Na+].Cl>C(#N)C.O>[C:1]([C:3]1[C:4]([O:15][CH3:16])=[CH:5][C:6]([O:13][CH3:14])=[C:7]([CH:12]=1)[C:8]([OH:10])=[O:9])#[N:2]参加物
6
実験手順
A 0.80 g portion of methyl 5-cyano-2,4-dimethoxybenzoate was dissolved in 8 ml of acetonitrile and 5 ml of water, and 7 ml of 2N sodium hydroxide aqueous solution was added, followed by stirring at room temperature for 6 hours. After completion of the reaction, the reaction solution was poured into 2N hydrochloric acid aqueous solution, extracted with chloroform and dried over anhydrous sodium sulfate. The solvent was evaporated under a reduced pressure to give 0.65 g of 5-cyano-2,4-dimethoxybenzoic acid.
後処理
- customAfter completion of the reaction
- extractionextracted with chloroform
- dry with materialdried over anhydrous sodium sulfate
- customThe solvent was evaporated under a reduced pressure
出典と根拠
- ORDレコード
- ord-eb612b2d13ea4bdeb292a31f636ec66c
- 出典データセット
- uspto-grants-1997_11
- 特許番号
- US05686482
反応ノート
読み込み中…