DL-alanine → 2-Methylpropyl 2-aminopropanoate hydrochloride
反応式
[NH2:1][CH:2]([C:4]([OH:6])=[O:5])[CH3:3].S(Cl)([Cl:9])=O.[CH2:11](O)[CH:12]([CH3:14])[CH3:13]>>[ClH:9].[CH2:11]([O:5][C:4](=[O:6])[CH:2]([CH3:3])[NH2:1])[CH:12]([CH3:14])[CH3:13]参加物
4
実験手順
A mixture of 35.64 g (0.4 mol) of D,L-alanine (Aldrich), 44 mL (0.6 mol) of thionyl chloride (Aldrich) and 200 mL of iso-butanol was refluxed for 1.5 hours. The volatiles were removed at reduced pressure at 90° C. under reduced pressure to give the title compound as an oil, which was used without further purification.
後処理
- temperaturewas refluxed for 1.5 hours
- customThe volatiles were removed at reduced pressure at 90° C. under reduced pressure
出典と根拠
- ORDレコード
- ord-4925e8544ee04f8dbe2b5bf9ea58b95b
- 出典データセット
- uspto-grants-2005_02
- 特許番号
- US06849650B2
反応ノート
読み込み中…