DL-alanine → 2-Methylpropyl 2-aminopropanoate hydrochloride

HRID 23018

反応式

HRID 23018 の反応式
[NH2:1][CH:2]([C:4]([OH:6])=[O:5])[CH3:3].S(Cl)([Cl:9])=O.[CH2:11](O)[CH:12]([CH3:14])[CH3:13]>>[ClH:9].[CH2:11]([O:5][C:4](=[O:6])[CH:2]([CH3:3])[NH2:1])[CH:12]([CH3:14])[CH3:13]

参加物

4

反応物 3

HCID 602DL-alanineHCID 6560IsobutanolHCID 24386Thionyl Chloride

生成物 1

HCID 862001092-Methylpropyl 2-aminopropanoate hydrochloride

実験手順

A mixture of 35.64 g (0.4 mol) of D,L-alanine (Aldrich), 44 mL (0.6 mol) of thionyl chloride (Aldrich) and 200 mL of iso-butanol was refluxed for 1.5 hours. The volatiles were removed at reduced pressure at 90° C. under reduced pressure to give the title compound as an oil, which was used without further purification.

後処理

  1. temperaturewas refluxed for 1.5 hours
  2. customThe volatiles were removed at reduced pressure at 90° C. under reduced pressure

出典と根拠

ORDレコード
ord-4925e8544ee04f8dbe2b5bf9ea58b95b
出典データセット
uspto-grants-2005_02
特許番号
US06849650B2

関連ノート

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