Trifluoroacetic acid → HCID 13603312、化合物
反応式
[CH2:1]([N:3]1[C:11]2[CH:10]=[C:9]3[CH:12](O)[CH2:13][O:14][C:8]3=[CH:7][C:6]=2[CH2:5][C:4]1=[O:16])[CH3:2].FC(F)(F)C(O)=O>C(#N)C>[CH2:1]([N:3]1[C:11]2[CH:10]=[C:9]3[CH:12]=[CH:13][O:14][C:8]3=[CH:7][C:6]=2[CH2:5][C:4]1=[O:16])[CH3:2]参加物
4
実験手順
To a slurry of 30.3 g. (0.138 mole) of 5-ethyl-3-hydroxy-6-oxo-2,3,6,7-tetrahydro-furo[2,3-f]indole in 950 ml. of acetonitrile at 25° C. was added 7 ml. of a 10% solution of trifluoroacetic acid in acetonitrile, and the reaction was allowed to stir at room temperature for 12 hours. The clear solution was evaporated to give a quantitative yield of the product. A small sample was recrystallized from hexane, m.p. 112°-113° C.
後処理
- customThe clear solution was evaporated
出典と根拠
- ORDレコード
- ord-e0829d7180024207bf7a152d7e41da97
- 出典データセット
- uspto-grants-1987_09
- 特許番号
- US04695571
反応ノート
読み込み中…