Hematoporphyrin → HCID 131715999、化合物
反応式
[CH3:1][C:2]1[C:20]([CH:21]([OH:23])[CH3:22])=[C:19]2[NH:24][C:3]=1[CH:4]=[C:5]1[C:38]([CH3:39])=[C:37]([CH2:40][CH2:41][C:42]([OH:44])=[O:43])[C:7]([CH:8]=[C:9]3[N:13]=[C:12]([CH:14]=[C:15]4[C:26]([CH:27]([OH:29])[CH3:28])=[C:25]([CH3:30])[C:17](=[CH:18]2)[NH:16]4)[C:11]([CH3:31])=[C:10]3[CH2:32][CH2:33][C:34]([OH:36])=[O:35])=[N:6]1>C1COCC1.C1CCC(NC2CCCCC2)CC1.CCOCC>[CH3:1][C:2]1[C:20]([CH:21]([OH:23])[CH3:22])=[C:19]2[NH:24][C:3]=1[CH:4]=[C:5]1[C:38]([CH3:39])=[C:37]([CH2:40][CH2:41][C:42]([OH:44])=[O:43])[C:7]([CH:8]=[C:9]3[N:13]=[C:12]([CH:14]=[C:15]4[C:26]([CH:27]([OH:29])[CH3:28])=[C:25]([CH3:30])[C:17](=[CH:18]2)[NH:16]4)[C:11]([CH3:31])=[C:10]3[CH2:32][CH2:33][C:34]([OH:36])=[O:35])=[N:6]1.[CH2:20]1[CH2:19][CH2:18][CH:17]([NH:16][CH:15]2[CH2:14][CH2:12][CH2:28][CH2:27][CH2:26]2)[CH2:25][CH2:30]1参加物
5
実験手順
To a solution of hematoporphyrin (1 g) in THF (30 ml), DCHA (2 ml) dissolved in ether (10 ml) was added, whereby the reaction proceeded. Ether was added to the reaction mixture. The precipitated crystals were collected by filtration and washed with ether to give hematoporphyrin DCHA salt (1.4 g). Yield, 90.0%.