Thionyl Chloride → Benzoyl chloride, 2,4-dichloro-5-fluoro-3-nitro-

HRID 231996

反応式

HRID 231996 の反応式
[Cl:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[C:9]([Cl:14])[C:8]([F:15])=[CH:7][C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:18])=O>CN(C)C=O>[Cl:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[C:9]([Cl:14])[C:8]([F:15])=[CH:7][C:3]=1[C:4]([Cl:18])=[O:5]

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 27342592,4-Dichloro-5-fluoro-3-nitrobenzoic acid

生成物 1

HCID 11818130Benzoyl chloride, 2,4-dichloro-5-fluoro-3-nitro-

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide触媒

実験手順

254 g (1 mol) of 2,4-dichloro-5-fluoro-3-nitrobenzoic acid are refluxed in 700 ml of thionyl chloride with addition of 3 drops of dimethylformamide until the gas evolution ceases. Excess thionyl chloride is removed by distillation, and the residue is fractionated in vacuo.

後処理

  1. customExcess thionyl chloride is removed by distillation

出典と根拠

ORDレコード
ord-7393af94a2b148a98950d68bf3c02574
出典データセット
uspto-grants-1989_07
特許番号
US04851160

関連ノート

読み込み中…