Acetonitrile → Ethyl 6-trimethylsilylethynyl-1,2-dihydro-2-(trifluoromethyl)-3-quinolinecarboxylate

HRID 2322898

反応式

[CH3:21][Si:22]([CH3:23])([CH3:24])[C:25]#[CH:26].[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33].[CH3:34][C:35]#[N:36].[Cu:78][I:79].[I:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[NH:8][CH:7]([C:12]([F:13])([F:14])[F:15])[C:6]([C:16](=[O:17])[O:18][CH2:19][CH3:20])=[CH:5]2.[Pd:37]([Cl:38])[Cl:39].[c:40]1([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[cH:54][cH:55][cH:56][cH:57][cH:58]1.[c:59]1([P:60]([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)[c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[cH:73][cH:74][cH:75][cH:76][cH:77]1>>[c:2]1([C:26]#[C:25][Si:22]([CH3:21])([CH3:23])[CH3:24])[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[NH:8][CH:7]([C:12]([F:13])([F:14])[F:15])[C:6]([C:16](=[O:17])[O:18][CH2:19][CH3:20])=[CH:5]2