Bromine → 2-Bromo-1-[4-(1H-imidazol-1-yl)phenyl]ethanone hydrobromide
反応式
[Br:1]Br.[N:3]1([C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:16])[CH3:15])=[CH:10][CH:9]=2)[CH:7]=[CH:6][N:5]=[CH:4]1>Br.C(O)(=O)C>[BrH:1].[Br:1][CH2:15][C:14]([C:11]1[CH:10]=[CH:9][C:8]([N:3]2[CH:7]=[CH:6][N:5]=[CH:4]2)=[CH:13][CH:12]=1)=[O:16]参加物
5
実験手順
Add bromine (5.71 mL, 0.111 mol) to a solution of 4'-(1H-imidazol-1-yl)acetophenone (20.75 g, 0.111 mol) in 30-32% HBr in acetic acid. Stir the mixture overnight and collect the crystals. Wash the crystals with ethanol (3×50 mL) and air dry for 2h at room temperature to afford the title compound.
後処理
- customcollect the crystals
- washWash the crystals with ethanol (3×50 mL) and air
- dry with materialdry for 2h at room temperature
出典と根拠
- ORDレコード
- ord-27f1074a998940f2a6cf78bb3d89b3ee
- 出典データセット
- uspto-grants-1989_07
- 特許番号
- US04851526
反応ノート
読み込み中…