Ethanolamine → 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-{[(E)-2-hydroxy-ethylimino]-methyl}-benzamide

反応式

[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[F:1][c:2]1[c:3]([NH:18][c:19]2[c:20]([F:26])[cH:21][c:22]([I:25])[cH:23][cH:24]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH:16]=[O:17])[c:14]1[F:15].[NH2:27][CH2:28][CH2:29][OH:30]>>[F:1][c:2]1[c:3]([NH:18][c:19]2[c:20]([F:26])[cH:21][c:22]([I:25])[cH:23][cH:24]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][c:13]([CH:16]=[N:27][CH2:28][CH2:29][OH:30])[c:14]1[F:15]

参加物

反応物 3

HCID 700Ethanolamine

HCID 8028Tetrahydrofuran

HCID 231323883,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-formyl-N-(2-hydroxy-ethoxy)-benzamide

生成物 1

HCID 593480293,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-{[(E)-2-hydroxy-ethylimino]-methyl}-benzamide

出典と根拠

ORDレコード: ord-007255e090294074bc3e3cadb43e1c17
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…