Nitric Acid → 4-Tert-butyl-1-methyl-2-nitrobenzene

HRID 23493

反応式

HRID 23493 の反応式
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].OS(O)(=O)=O.[N+:17]([O-])([OH:19])=[O:18]>O>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([CH3:11])=[C:9]([N+:17]([O-:19])=[O:18])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2]

参加物

5

反応物 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 73904-tert-Butyltoluene

生成物 1

HCID 109544154-Tert-butyl-1-methyl-2-nitrobenzene

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Nitration was performed as described in General Method 12 using tert-butyl-4-methylbenzene (25 g), concentrated H2SO4 (92 g), 70% HNO3 (82 g), and H2O (25 g). The crude product was purified via distillation under vacuum.

後処理

  1. distillationThe crude product was purified via distillation under vacuum

出典と根拠

ORDレコード
ord-28047e1787ec4cb588412d11eb80d13c
出典データセット
uspto-grants-2005_02
特許番号
US06852711B2

関連ノート

読み込み中…