2,4-Dinitrobenzoic acid → 2,4-Dinitrobenzamide

HRID 235060

反応式

HRID 235060 の反応式
[N+:1]([C:4]1[CH:12]=[C:11]([N+:13]([O-:15])=[O:14])[CH:10]=[CH:9][C:5]=1[C:6](O)=[O:7])([O-:3])=[O:2].C(Cl)(=O)C(Cl)=O.[NH4+:22].[OH-]>>[N+:1]([C:4]1[CH:12]=[C:11]([N+:13]([O-:15])=[O:14])[CH:10]=[CH:9][C:5]=1[C:6]([NH2:22])=[O:7])([O-:3])=[O:2]

参加物

4

反応物 3

HCID 118802,4-Dinitrobenzoic acidHCID 14923Ammonium HydroxideHCID 65578Oxalyl chloride

生成物 1

HCID 37335182,4-Dinitrobenzamide収率 89%

実験手順

2,4-Dinitrobenzoic acid (8.17 g, 38.5 mmol) was treated with oxalyl chloride (3.90 mL, 44.7 mmol). The resulting acid chloride was treated with saturated NH4OH solution (200 mL) to yield the title compound (7.25 g, 89%). m.p. 202°-204° C. 1H NMR (300 MHz, DMSO) δ8.75 (d, 1H), 8.58 (dd, 1H), 8.48 (br s, 1H), 7.99 (br s, 1H), 7.91 (d, 1H), 5.50-6.20 (br s, 2H). MS (DCI/NH3) m/e 229 (M+NH4)+.

出典と根拠

ORDレコード
ord-31a6f5a7f71c4d809ae281e01e1ca844
出典データセット
uspto-grants-1997_01
特許番号
US05597823

関連ノート

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