Thionyl Chloride → 10-Chloro-1-decene
反応式
[CH2:1](O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH:9]=[CH2:10].S(Cl)([Cl:14])=O>N1C=CC=CC=1.ClCCl>[Cl:14][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH:9]=[CH2:10]参加物
5
実験手順
10 drops of pyridine was added to 26.0 g of 9-decene-1-ol and the mixture was placed in an eggplant type flask. Into the flask was then dropped 24.0 g of thionyl chloride while cooling with ice. After dropping thionyl chloride, reaction was carried out for 8.5 hours at 70° C. After the reaction, the resulting reaction solution was diluted with dichloromethane and was washed with an aqueous potassium hydroxide solution. The organic phase was dried over magnesium sulfate and was then concentrated under reduced pressure. The resulting residue was purified by column chromatography to obtain 27.7 g of 10-chloro-1-decene. (Yield: 95%).
後処理
- customthe mixture was placed in an eggplant type flask
- temperaturewhile cooling with ice
- customAfter the reaction
- customthe resulting reaction solution
- washwas washed with an aqueous potassium hydroxide solution
- dry with materialThe organic phase was dried over magnesium sulfate
- concentrationwas then concentrated under reduced pressure
- customThe resulting residue was purified by column chromatography
出典と根拠
- ORDレコード
- ord-756996190d1a437cae52fdab262cc154
- 出典データセット
- uspto-grants-1989_10
- 特許番号
- US04877858
反応ノート
読み込み中…