1-Iodohexadecane → 1-Hexadecyl-2-methoxybenzene

HRID 235721

反応式

HRID 235721 の反応式
[CH2:1](I)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].Br[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[O:25][CH3:26].[Mg]>O1CCCC1>[CH2:1]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[O:25][CH3:26])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

参加物

5

反応物 3

HCID 110071-IodohexadecaneHCID 113582-BromoanisoleHCID 5462224Magnesium

生成物 1

HCID 202186521-Hexadecyl-2-methoxybenzene収率 102%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

To a refluxing solution of about 35.3 g of hexadecyl iodide in tetrahydrofuran was added a solution of about 37.4 g of bromoanisole and about 4.86 g of magnesium in tetrahydrofuran which had been refluxed for about 2 hours. An about 10 ml portion of about 0.1M lithium cupric chloride was added, the mixture was refluxed about 2 hours and stirred at room temperature for about 16 hours giving about 34 g of the desired reagent.

後処理

  1. temperaturehad been refluxed for about 2 hours
  2. temperaturethe mixture was refluxed about 2 hours

出典と根拠

ORDレコード
ord-79e0827f7dc4487992b562bca3ef6639
出典データセット
uspto-grants-1987_02
特許番号
US04640913

関連ノート

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