Ethyl bromoacetate → HCID 13773143、化合物
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][C:18]=1[Cl:19])[C:5]([NH:7][CH2:8][C:9]([C:11]1[CH:15]=[CH:14][O:13][CH:12]=1)=[O:10])=[O:6].[H-].[Na+].Br[CH2:23][C:24]([O:26][CH2:27][CH3:28])=[O:25]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][C:18]=1[Cl:19])[C:5]([NH:7][CH:8]([C:9]([C:11]1[CH:15]=[CH:14][O:13][CH:12]=1)=[O:10])[CH2:23][C:24]([O:26][CH2:27][CH3:28])=[O:25])=[O:6]参加物
4
実験手順
7.6 g of N-(3,4-dichlorobenzoyl)-(3-furylcarbonyl)methylamine, 1.2 g of 61% sodium hydride and 4.7 g of ethyl bromoacetate are treated in the same manner as described in Preparation 1-(2). 9.0 g of ethyl 3-(3,4-dichlorobenzoylamino)-3-(3-furylcarbonyl)propionate are thereby obtained. Yield: 91.9%
後処理
- customas described in Preparation 1-(2)