Hydrazine hydrate (1:1) → 6-(4-Fluorophenyl)-3-hydrazinyl-1,2,4-triazine

HRID 237097ノート

反応式

HRID 237097 の反応式
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([F:14])=[CH:10][CH:9]=2)=[CH:6][N:7]=1.O.[NH2:16][NH2:17]>N1C=CC=CC=1>[NH:16]([C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([F:14])=[CH:10][CH:9]=2)=[CH:6][N:7]=1)[NH2:17]

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 213152193-Chloro-6-(4-fluorophenyl)-1,2,4-triazine

生成物 1

HCID 213152186-(4-Fluorophenyl)-3-hydrazinyl-1,2,4-triazine

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

A solution of 9.8 g. of 3-chloro-6-(p-fluorophenyl)-1,2,4-triazine in 125 ml. of pyridine is cooled to 0° C. and 15 ml. of hydrazine hydrate is added. The mixture is stirred at room temperature for one hour and then poured into icewater. The solid is recovered by filtration and washed with ethanol, giving 3-hydrazino-6-(p-fluorophenyl)-1,2,4-triazine as an orange solid.

後処理

  1. additionpoured into icewater
  2. filtrationThe solid is recovered by filtration
  3. washwashed with ethanol

出典と根拠

ORDレコード
ord-c279d885aaa140f9bb11cee7ab004c31
出典データセット
uspto-grants-1979_06
特許番号
US04159375

反応ノート

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