Dimethylformamide → HCID 22803977、化合物
反応式
[OH:1][CH2:2][C@@H:3]1[CH:18]=[C:17]2[C@@H:7]([CH2:8][C:9]3[C:19]4[C:12](=[CH:13][CH:14]=[CH:15][C:16]2=4)[NH:11][CH:10]=3)[N:5]([CH3:6])[CH2:4]1.CN(C)C=O>[Pd].N1C=CC=CC=1>[OH:1][CH2:2][C@@H:3]1[CH:18]=[C:17]2[C@@H:7]([CH2:8][CH:9]3[C:19]4[C:12](=[CH:13][CH:14]=[CH:15][C:16]2=4)[NH:11][CH2:10]3)[N:5]([CH3:6])[CH2:4]1参加物
5
実験手順
catalytically hydrogenating under a pressure of 1 to 5 bar, a reaction mixture comprising lysergol and least one aprotic solvent containing a tertiary nitrogen a solvent mixture of N,N-dimethylformamide and pyridine and a 5 to 10% palladium catalyst applied on activated carbon, at a temperature between 40° C. and the boiling point of the reaction mixture, to form dihydrolysergol; and
後処理
- customapplied on activated carbon, at a temperature between 40° C.
出典と根拠
- ORDレコード
- ord-ad66960c942e470b87e1f50a3f3616dd
- 出典データセット
- uspto-grants-1992_03
- 特許番号
- US05097031
反応ノート
読み込み中…