1-Phenylpiperazine → alpha-{[1-(4-Phenylpiperazinyl)]methyl}benzeneacetic acid

HRID 2379693

反応式

HRID 2379693 の反応式
[C:1]1([N:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:13]([OH:23])(=[O:22])[C:14]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[CH2:15]>C(O)C>[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([CH2:15][CH:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:13]([OH:23])=[O:22])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 70961-PhenylpiperazineHCID 68114Atropic acid

生成物 1

HCID 19433570alpha-{[1-(4-Phenylpiperazinyl)]methyl}benzeneacetic acid

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

1-Phenylpiperazine and atropic acid in ethanol is heated under reflux for 18h, cooled to room temperature, and evaporated in vacuo. The solid is triturated with acetone to give the title product.

後処理

  1. customevaporated in vacuo
  2. customThe solid is triturated with acetone

出典と根拠

ORDレコード
ord-c44b4576b93d468db51b1b96c49107ff
出典データセット
uspto-grants-1994_11
特許番号
US05364849

関連ノート

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